SEC Based Method for Size Determination of Immune Complexes of Therapeutic Antibodies in Animal Matrix

Therapeutic monoclonal antibodies (mAbs) represent a milestone in pharmacological development. Their superiority is based on the combination of high specificity, low toxicity, and long half-life that characterizes biologics. If biologics have Achilles’ heel, it is their potential immunogenicity. To...

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Bibliographic Details
Main Authors: Marta Boysen, Laura Schlicksupp, Ingeborg Dreher, Ralf Loebbert, Mario Richter
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2016/9096059
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