Rabson-Mendenhall syndrome presented as severe acanthosis nigricans in an infant harboring novel mutations in the INSR gene: a case report

BackgroundRabson-Mendenhall Syndrome (RMS), a rare hereditary form of insulin resistance, is marked by severe hyperinsulinemia and early-onset acanthosis nigricans (AN) during childhood.Case presentationA case of a 15-month-old girl was reported, presenting with widespread acanthosis nigricans, grow...

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Bibliographic Details
Main Authors: Shi Yan, Yu Sheng, Hai-zhen Hui, Chun-yan Zhou, De-ming Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pediatrics
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Online Access:https://www.frontiersin.org/articles/10.3389/fped.2025.1511429/full
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