“Sensitive and sustainable stability-indicating RP-HPLC method for simultaneous assay and impurity profiling of amitriptyline HCl: green metric, RGB model and forced degradation study"

Abstract A novel, sensitive, sustainable, and stability-indicating reverse-phase high-performance liquid chromatography method was developed to isolate and quantify amitriptyline hydrochloride and its impurities present in pharmaceuticals. The method employed an L1 column under isocratic elution con...

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Bibliographic Details
Main Authors: Anand Radheshyam Tiwari, Sushama Raju Ambadekar, Vijay Arjun Bagul
Format: Article
Language:English
Published: Springer 2025-06-01
Series:Discover Chemistry
Subjects:
Online Access:https://doi.org/10.1007/s44371-025-00218-8
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