First-line pazopanib in patients with metastatic epithelioid hemangioendothelioma: a retrospective single-center analysis

First-line pazopanib in patients with metastatic epithelioid hemangioendothelioma: a retrospective single-center analysis

Abstract Purpose Epithelioid hemangioendothelioma (EHE) represents an ultra-rare, translocated vascular sarcoma with a heterogeneous course of disease. The optimal systemic treatment for patients with advanced EHE remains unclear. We sought to evaluate the value of pazopanib (PAZ) as a first-line tr...

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Main Authors: Anton Burkhard-Meier, Vera Valerie Rechenauer, Vindi Jurinovic, Markus Albertsmeier, Michael Hoberger, Hans Roland Dürr, Alexander Klein, Thomas Knösel, Wolfgang G. Kunz, Andreas Mock, Ada Pusztai, Michael Völkl, Michael von Bergwelt-Baildon, Lars H. Lindner, Dorit Di Gioia, Luc M. Berclaz
Format: Article
Language:English
Published: Springer 2025-04-01
Series:Journal of Cancer Research and Clinical Oncology
Subjects:
Epithelioid hemangioendothelioma
Rare cancers
Metastasis
Pazopanib
Targeted therapy
Online Access:https://doi.org/10.1007/s00432-025-06208-8
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https://doi.org/10.1007/s00432-025-06208-8

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