Siponimod supports remyelination in the non-supportive environment

Siponimod supports remyelination in the non-supportive environment

Abstract Inflammatory demyelination, a hallmark of multiple sclerosis (MS) lesions, leads to functional impairments and progressive axonal loss over time. Although remyelination is thought to protect axons, endogenous regenerative processes are often incomplete or fail entirely in many MS patients....

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Bibliographic Details
Main Authors: Johann Krüger, Newshan Behrangi, David Schliep, Leo Heinig, Elise Vankriekelsvenne, Nicole Wigger, Markus Kipp
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Multiple sclerosis
Cuprizone
Siponimod
Remyelination
Sphingosine-1-phosphate
Online Access:https://doi.org/10.1038/s41598-025-87825-8
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https://doi.org/10.1038/s41598-025-87825-8

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