Robust generation of oligodendrocyte progenitors from human neural stem cells and engraftment in experimental demyelination models in mice.

<h4>Background</h4>Cell-based therapy holds great promises for demyelinating diseases. Human-derived fetal and adult oligodendrocyte progenitors (OPC) gave encouraging results in experimental models of dysmyelination but their limited proliferation in vitro and their potential immunogeni...

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Bibliographic Details
Main Authors: Margherita Neri, Claudio Maderna, Daniela Ferrari, Chiara Cavazzin, Angelo L Vescovi, Angela Gritti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0010145&type=printable
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