White matter dysfunction in Alzheimer’s disease is associated with disease-related transcriptomic signatures

White matter dysfunction in Alzheimer’s disease is associated with disease-related transcriptomic signatures

Abstract While anatomical white matter (WM) alterations in Alzheimer’s disease (AD) are well-established, functional WM dysregulation remains rarely investigated. The current study examines WM functional connectivity and network properties alterations in AD and mild cognitive impairment (MCI) and fu...

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Main Authors: Yilu Li, Guanyu Zhou, Jinzhong Peng, Lin Liu, Fanyu Zhang, Yasser Iturria-Medina, Dezhong Yao, Bharat B. Biswal, Pan Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08177-7
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https://doi.org/10.1038/s42003-025-08177-7

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