Fecal Microbiota Transplantation Using Donor Stool Obtained from Exercised Mice Suppresses Colonic Tumor Development Induced by Azoxymethane in High-Fat Diet-Induced Obese Mice

Fecal Microbiota Transplantation Using Donor Stool Obtained from Exercised Mice Suppresses Colonic Tumor Development Induced by Azoxymethane in High-Fat Diet-Induced Obese Mice

The gut microbiota plays an important role in the development of colorectal tumors. However, the underlying mechanisms remain unclear. In this study, we examined the effects of fecal microbiota transplantation (FMT) on azoxymethane (AOM)-induced colorectal tumors in obese mice. We divided the study...

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Main Authors: Hiroshi Matsumoto, Tingting Gu, Shogen Yo, Momoyo Sasahira, Shuzo Monden, Takehiro Ninomiya, Motoyasu Osawa, Osamu Handa, Eiji Umegaki, Akiko Shiotani
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Microorganisms
Subjects:
fecal microbiota transplantation (FMT)
colorectal cancer
obesity
exercise
high-fat diet
Online Access:https://www.mdpi.com/2076-2607/13/5/1009
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