Systems metabolic engineering of Escherichia coli for L‐threonine production

Abstract Amino‐acid producers have traditionally been developed by repeated random mutagenesis owing to the difficulty in rationally engineering the complex and highly regulated metabolic network. Here, we report the development of the genetically defined L‐threonine overproducing Escherichia coli s...

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Bibliographic Details
Main Authors: Kwang Ho Lee, Jin Hwan Park, Tae Yong Kim, Hyun Uk Kim, Sang Yup Lee
Format: Article
Language:English
Published: Springer Nature 2007-12-01
Series:Molecular Systems Biology
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Online Access:https://doi.org/10.1038/msb4100196
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