Paneth cells in intestinal homeostasis and tissue injury.

Adult stem cell niches are often co-inhabited by cycling and quiescent stem cells. In the intestine, lineage tracing has identified Lgr5(+) cells as frequently cycling stem cells, whereas Bmi1(+), mTert(+), Hopx(+) and Lrig1(+) cells appear to be more quiescent. Here, we have applied a non-mutagenic...

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Bibliographic Details
Main Authors: Sabrina Roth, Patrick Franken, Andrea Sacchetti, Andreas Kremer, Kurt Anderson, Owen Sansom, Riccardo Fodde
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0038965&type=printable
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