Chronic Intestinal Inflammation and Microbial Dysbiosis Are Associated With Female Reproductive Outcomes in a Mouse Model of Inflammatory Bowel Disease

Chronic Intestinal Inflammation and Microbial Dysbiosis Are Associated With Female Reproductive Outcomes in a Mouse Model of Inflammatory Bowel Disease

Background and Aims: The mechanism for increased infertility and adverse pregnancy outcomes in women with active inflammatory bowel disease is unknown. We aimed to create a murine model of chronic gut inflammation to study the pathogenesis of reproductive outcomes in inflammatory bowel disease. Meth...

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Bibliographic Details
Main Authors: Maria Martell, Clare F. Quarnstrom, Alexander Khoruts, Vaiva Vezys, Christopher Staley, Eugenia Shmidt
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Gastro Hep Advances
Subjects:
Inflammatory Bowel Disease
Female Infertility
Intestinal Inflammation
Gut Microbiome
Online Access:http://www.sciencedirect.com/science/article/pii/S2772572325000573
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