Format-tuning of in vivo-launched bispecific T cell engager enhances efficacy against renal cell carcinoma

Format-tuning of in vivo-launched bispecific T cell engager enhances efficacy against renal cell carcinoma

Background Advanced clear cell renal cell carcinoma (ccRCC) is a prevalent kidney cancer for which long-term survival rates are abysmal, though immunotherapies are showing potential. Not yet clinically vetted are bispecific T cell engagers (BTEs) that activate T cell-mediated cancer killing through...

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Main Authors: Carl H June, David Weiner, Christopher A Chuckran, Daniel Park, Ryan P O’Connell, Kevin Liaw, Nils Wellhausen, Pratik S Bhojnagarwala, Devivasha Bordoloi, Nicholas Shupin, Daniel Kulp
Format: Article
Language:English
Published: BMJ Publishing Group 2024-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/12/6/e008733.full
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https://jitc.bmj.com/content/12/6/e008733.full

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