PPAR-γ Activation Exerts an Anti-inflammatory Effect by Suppressing the NLRP3 Inflammasome in Spinal Cord-Derived Neurons

Persistent inflammation disrupts functional recovery after spinal cord injury (SCI). Peroxisome proliferator-activated receptor gamma (PPAR-γ) activation promotes functional recovery in SCI rats by inhibiting inflammatory cascades and increasing neuronal survival. We sought to clarify the relationsh...

Full description

Saved in:
Bibliographic Details
Main Authors: Qing-Qi Meng, Zhen-Cheng Feng, Xing-Liang Zhang, Li-Qiong Hu, Min Wang, Hai-Feng Zhang, Si-Ming Li
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2019/6386729
Tags: Add Tag
No Tags, Be the first to tag this record!