A multilevel screening pipeline in zebrafish identifies therapeutic drugs for GAN

Abstract Giant axonal neuropathy (GAN) is a fatal neurodegenerative disorder for which there is currently no treatment. Affecting the nervous system, GAN starts in infancy with motor deficits that rapidly evolve toward total loss of ambulation. Using the gan zebrafish model that reproduces the loss...

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Bibliographic Details
Main Authors: Léa Lescouzères, Cédric Hassen‐Khodja, Anaïs Baudot, Benoît Bordignon, Pascale Bomont
Format: Article
Language:English
Published: Springer Nature 2023-05-01
Series:EMBO Molecular Medicine
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Online Access:https://doi.org/10.15252/emmm.202216267
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