In-vitro immune-modulation of triple-negative breast cancer through targeting miR-30a-5p/MALAT1 axis using nano-PDT combinational approach

In-vitro immune-modulation of triple-negative breast cancer through targeting miR-30a-5p/MALAT1 axis using nano-PDT combinational approach

Background: Triple negative breast cancer (TNBC) is an immunogenic tumor; however, its tumor immune microenvironment (TIME) is densely packed with immune suppressive cytokines and immune checkpoints. The immune-suppressive features of TNBC TIME represent a considerable obstacle to any immunotherapeu...

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Bibliographic Details
Main Authors: Asmaa Ramzy, Mohammad Abdel-Halim, Tamer Manie, Noha M. Elemam, Samar Mansour, Rana A. Youness, Aya Sebak
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Translational Oncology
Subjects:
Tumor microenvironment
PDT
TNBC
Nanomaterials
MALAT1
Immunotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523325000968
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