Active Vitamin D Ameliorates Arsenite-Induced Thyroid Dysfunction in Sprague–Dawley Rats by Inhibiting the Toll-like Receptor 4/NF-KappaB-Mediated Inflammatory Response

Active Vitamin D Ameliorates Arsenite-Induced Thyroid Dysfunction in Sprague–Dawley Rats by Inhibiting the Toll-like Receptor 4/NF-KappaB-Mediated Inflammatory Response

Arsenic, a well-known environmental endocrine disruptor, exerts interference on the body’s endocrine system. Our previous investigations have demonstrated that chronic exposure to sodium arsenite (NaAsO<sub>2</sub>) can induce thyroid damage and dysfunction in Sprague–Dawley (SD) rats. V...

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Bibliographic Details
Main Authors: Hui Li, Jie Xiang, Qian Song, Ying Jin, Meitong Zhou, Lili Fan, Dapeng Wang
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Toxics
Subjects:
sodium arsenite
thyrotoxicity
vitamin D
thyroid hormone
TLR4/NF-κB signaling pathway
Online Access:https://www.mdpi.com/2305-6304/12/12/887
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