Entinostat in combination with nivolumab for patients with advanced cholangiocarcinoma: a phase 2 clinical trial

Entinostat in combination with nivolumab for patients with advanced cholangiocarcinoma: a phase 2 clinical trial

Abstract Introduction Cholangiocarcinoma (CCA) is an aggressive cancer characterized by high metastatic potential and poor prognosis. Recent advances in understanding the molecular biology of CCA have led to the development of novel therapeutic strategies. However, the immunosuppressive tumor microe...

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Main Authors: Elsa Hallab, Jennifer N. Durham, Rosalind Walker, Leslie Cope, Soren Charmsaz, Nicole E. Gross, Dimitrios N. Sidiropoulos, Alexei Hernandez, James Leatherman, Sarah Mitchell, Mark Yarchoan, Won Jin Ho, Nilofer S. Azad, Marina Baretti
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Epigenetics Communications
Online Access:https://doi.org/10.1186/s43682-025-00037-z
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https://doi.org/10.1186/s43682-025-00037-z

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