Pregnancy exacerbates neutrophil responses in murine lungs and alters gut microbiota composition after cigarette smoke exposure

Pregnancy exacerbates neutrophil responses in murine lungs and alters gut microbiota composition after cigarette smoke exposure

IntroductionAir pollution, particularly environmental tobacco smoke, poses significant health risks, especially to pregnant women and their infants. This study explores the difference in response to cigarette smoke (CS) exposure between pregnant and non-pregnant mice by examining lung transcriptomic...

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Main Authors: Ali Dehghani, Lei Wang, Johan Garssen, Eirini Styla, Thea Leusink-Muis, Ingrid van Ark, Gert Folkerts, Jeroen van Bergenhenegouwen, Saskia Braber
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
pregnancy
air pollution
environmental tobacco smoke
neutrophil chemotaxis
gut microbiota
lung transcriptomics
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1590290/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1590290/full

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