Immunosenescence markers in T- and NK-cells according to the CD4/CD8 ratio in successfully treated people living with HIV

Immunosenescence markers in T- and NK-cells according to the CD4/CD8 ratio in successfully treated people living with HIV

IntroductionThe CD4/CD8 ratio has emerged as a useful indicator of immune dysfunction and comorbid conditions in people living with HIV (PLWH). However, its optimal cut-off value is unclear. We explored the correlation between the CD4/CD8 ratio, immunosenescence markers and comorbid conditions.Metho...

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Bibliographic Details
Main Authors: Matteo Vassallo, Jacques Durant, Sami Addou, Michel Ticchioni, Roxane Fabre, David Chirio, Alissa Naqvi, Eric Cua, Leslie Ameil, Maeva Godemert, Christian Pradier, Michel Carles
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Medicine
Subjects:
HIV
CD4/CD8 ratio
immunosenescence
comorbidity
immune activation
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1562537/full
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https://www.frontiersin.org/articles/10.3389/fmed.2025.1562537/full

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