An antisense oligomer conjugate with unpredicted bactericidal activity against Fusobacterium nucleatum

ABSTRACT Fusobacteria are commensal members of the oral microbiome that can spread from their primary niche and colonize distal sites in the human body. Their enrichment in colorectal and breast cancer tissue has been associated with tumor growth, metastasis, and chemotherapeutic resistance. The use...

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Bibliographic Details
Main Authors: Valentina Cosi, Jakob Jung, Linda Popella, Falk Ponath, Chandradhish Ghosh, Lars Barquist, Jörg Vogel
Format: Article
Language:English
Published: American Society for Microbiology 2025-06-01
Series:mBio
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Online Access:https://journals.asm.org/doi/10.1128/mbio.00524-25
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