The effect of prebiotic fibre on the gut microbiome and surgical outcomes in patients with prosthetic joint infection (PENGUIN) - study protocol for a randomised, double-blind, placebo-controlled trial (ACTRN12623001273673)

The effect of prebiotic fibre on the gut microbiome and surgical outcomes in patients with prosthetic joint infection (PENGUIN) - study protocol for a randomised, double-blind, placebo-controlled trial (ACTRN12623001273673)

Abstract Background Prosthetic Joint Infection (PJI) is the most devastating complication of arthroplasty surgery and affects 1–5% of patients. Despite strict adherence to aseptic protocols and preventive measures, infection is the most common reason for revision arthroplasty, and the incidence is i...

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Main Authors: Deepti K. Sharma, Balamurugan Ramadass, Stuart A. Callary, Anthony Meade, Rishikesh Dash, Robyn Clothier, Gerald J. Atkins, L. Bogdan Solomon, Boopalan Ramasamy
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Nutrition Journal
Subjects:
Prosthetic joint infection
Gut dysbiosis
Resistant starch
Prebiotic fibre
Two-stage revision
Arthroplasty
Online Access:https://doi.org/10.1186/s12937-024-01034-z
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https://doi.org/10.1186/s12937-024-01034-z

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