Fused oxazepine-naphthoquinones as novel cytotoxic agents with diverse modes of action in yeast
The naphthoquinone moiety is commonly found in numerous natural cytotoxic compounds with diverse and pleiotropic modes of action (MOAs). The moiety can exist as a standalone pharmacophore or combined with other pharmacophores to enrich their MOAs. Here, we report that the synthetic fusion of naphtho...
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| Main Authors: | Laura Anaissi-Afonso, Silvia Santana-Sosa, Isabel Lorenzo-Castrillejo, Grant McNaughton-Smith, Félix Machín |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-12-01
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| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024171368 |
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