Minicircle-based vaccine induces potent T-cell and antibody responses against hepatitis C virus

Minicircle-based vaccine induces potent T-cell and antibody responses against hepatitis C virus

Abstract An effective vaccine against hepatitis C virus (HCV) should elicit both humoral and cellular immune responses. Previously, we characterized a bivalent vaccine candidate against hepatitis B (HBV) and HCV using chimeric HBV-HCV virus-like particles (VLP), in which the highly conserved epitope...

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Bibliographic Details
Main Authors: Anna Czarnota, Aleksandra Raszplewicz, Aleksandra Sławińska, Krystyna Bieńkowska-Szewczyk, Katarzyna Grzyb
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
HCV
HBV
Vaccine
Minicircle
DNA
VLP
Online Access:https://doi.org/10.1038/s41598-024-78049-3
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https://doi.org/10.1038/s41598-024-78049-3

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