Accurate quantitative wide-field fluorescence microscopy of 3-D spheroids

Hundreds of commercially available fluorescent dyes are used to quantify a wide range of biological functions of cells in culture, and their use has been a mainstay of basic research, toxicity testing, and drug discovery. However, nearly all of these dyes have been optimized for use on cells culture...

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Bibliographic Details
Main Authors: Elizabeth Leary, Claire Rhee, Benjamin Wilks, Jeffrey R. Morgan
Format: Article
Language:English
Published: Taylor & Francis Group 2016-11-01
Series:BioTechniques
Subjects:
Online Access:https://www.future-science.com/doi/10.2144/000114472
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