Hypoxia reconstructed colorectal tumor microenvironment weakening anti-tumor immunity: construction of a new prognosis predicting model through transcriptome analysis

Hypoxia reconstructed colorectal tumor microenvironment weakening anti-tumor immunity: construction of a new prognosis predicting model through transcriptome analysis

BackgroundHypoxia in the tumor microenvironment (TME) plays a pivotal role in the progression and prognosis of colorectal cancer (CRC). However, effective methods for assessing TME hypoxia remain lacking. This study aims to develop a novel hypoxia-related prognostic score (HPS) based on hypoxia-asso...

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Bibliographic Details
Main Authors: Ruizhi Zhang, Yisong Gao, Chong Li, Ruikang Tao, Gan Mao, Tianyu Song, Wenxiang Nie, Suao Liu, Kaixiong Tao, Wei Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
hypoxia
colorectal cancer
tumor microenvironment immunity
extracellular matrix
WGCNA
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1425687/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1425687/full

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