Machine learning analysis of rivaroxaban solubility in mixed solvents for application in pharmaceutical crystallization

Abstract This study investigates the use of machine learning models to predict solubility of rivaroxaban in binary solvents based on temperature (T), mass fraction (w), and solvent type. Using a dataset with over 250 data points and including solvents encoded with one-hot encoding, four models were...

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Bibliographic Details
Main Authors: Mohammed Alqarni, Ali Alqarni
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-84741-1
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