Rosiglitazone Inhibits Adrenocortical Cancer Cell Proliferation by Interfering with the IGF-IR Intracellular Signaling

Rosiglitazone Inhibits Adrenocortical Cancer Cell Proliferation by Interfering with the IGF-IR Intracellular Signaling

Rosiglitazone (RGZ), a thiazolidinedione ligand of the peroxisome proliferator-activated receptor (PPAR)-γ, has been recently described as possessing antitumoral properties. We investigated RGZ effect on cell proliferation in two cell line models (SW13 and H295R) of human adrenocortical carcinoma (A...

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Main Authors: Giulia Cantini, Adriana Lombardi, Elisabetta Piscitelli, Giada Poli, Elisabetta Ceni, Sara Marchiani, Tonino Ercolino, Andrea Galli, Mario Serio, Massimo Mannelli, Michaela Luconi
Format: Article
Language:English
Published: Wiley 2008-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2008/904041
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http://dx.doi.org/10.1155/2008/904041

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