Mechanism and Kinetics of HIV-1 Protease Activation

The HIV-1 protease is a critical enzyme for viral replication. Because protease activity is necessary to generate mature infectious virions, it is a primary target of antiretroviral treatment. Here, we provide an overview of the mechanisms regulating protease activation and the methods available to...

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Bibliographic Details
Main Authors: Caroline O. Tabler, John C. Tilton
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/16/12/1826
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