DNA methylation signatures of severe RSV infection in infants: evidence from non-invasive saliva samples

DNA methylation signatures of severe RSV infection in infants: evidence from non-invasive saliva samples

Abstract Background Respiratory syncytial virus (RSV) poses significant morbidity and mortality risks in childhood, particularly for previously healthy infants admitted to hospitals lacking predisposing risk factors for severe disease. This study aimed to investigate the role of the host epigenome i...

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Main Authors: Sara Pischedda, Alberto Gómez-Carballa, Jacobo Pardo-Seco, Sandra Viz-Lasheras, Alba Camino-Mera, Xabier Bello, María José Curras-Tuala, Irene Rivero-Calle, Ana I. Dacosta-Urbieta, Federico Martinón-Torres, Antonio Salas, GENDRES Consortium
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Epigenetics & Chromatin
Subjects:
Respiratory syncytial virus
Severity
Buccal swab
DNA methylation
Epigenetic biomarkers
Online Access:https://doi.org/10.1186/s13072-025-00587-5
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https://doi.org/10.1186/s13072-025-00587-5

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