Detection of alpha-rod protein repeats using a neural network and application to huntingtin.

Detection of alpha-rod protein repeats using a neural network and application to huntingtin.

A growing number of solved protein structures display an elongated structural domain, denoted here as alpha-rod, composed of stacked pairs of anti-parallel alpha-helices. Alpha-rods are flexible and expose a large surface, which makes them suitable for protein interaction. Although most likely origi...

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Main Authors: Gareth A Palidwor, Sergey Shcherbinin, Matthew R Huska, Tamas Rasko, Ulrich Stelzl, Anup Arumughan, Raphaele Foulle, Pablo Porras, Luis Sanchez-Pulido, Erich E Wanker, Miguel A Andrade-Navarro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-03-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000304&type=printable
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https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000304&type=printable

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