Temporal RAGE Over-Expression Disrupts Lung Development by Modulating Apoptotic Signaling

Temporal RAGE Over-Expression Disrupts Lung Development by Modulating Apoptotic Signaling

Receptors for advanced glycation end products (RAGE) are multiligand cell surface receptors found most abundantly in lung tissue. This study sought to evaluate the role of RAGE in lung development by using a transgenic (TG) mouse model that spatially and temporally controlled RAGE overexpression. Hi...

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Bibliographic Details
Main Authors: Derek M. Clarke, Madison N. Kirkham, Logan B. Beck, Carrleigh Campbell, Hayden Alcorn, Benjamin T. Bikman, Juan A. Arroyo, Paul R. Reynolds
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Current Issues in Molecular Biology
Subjects:
RAGE
lung
embryo
transgenic
apoptosis
Online Access:https://www.mdpi.com/1467-3045/46/12/867
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