Transcriptomic and proteomic integrated analysis reveals molecular mechanisms of 3D bioprinted vaginal scaffolds in vaginal regeneration

Transcriptomic and proteomic integrated analysis reveals molecular mechanisms of 3D bioprinted vaginal scaffolds in vaginal regeneration

Abstract 3D Bioprinting technology has been applied to vaginal reconstruction with satisfactory results. Understanding the transcriptome and proteome of regenerated vaginas is essential for knowing how biomaterials and seed cells contribute to vaginal regeneration. There are no reports on the system...

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Bibliographic Details
Main Authors: Xuemei Zhang, Jiahua Zheng, Liye Zhang, Jingkun Zhang, Li Feng, Lin Zhang, Xianghua Huang
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Vaginal reconstruction
Biological scaffold
Bone marrow-derived mesenchymal stem cells
Proteomics
Transcriptomics
Online Access:https://doi.org/10.1038/s41598-025-00507-3
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https://doi.org/10.1038/s41598-025-00507-3

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