Cell cycle genes are the evolutionarily conserved targets of the E2F4 transcription factor.

Cell cycle genes are the evolutionarily conserved targets of the E2F4 transcription factor.

Maintaining quiescent cells in G0 phase is achieved in part through the multiprotein subunit complex known as DREAM, and in human cell lines the transcription factor E2F4 directs this complex to its cell cycle targets. We found that E2F4 binds a highly overlapping set of human genes among three dive...

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Main Authors: Caitlin M Conboy, Christiana Spyrou, Natalie P Thorne, Elizabeth J Wade, Nuno L Barbosa-Morais, Michael D Wilson, Arindam Bhattacharjee, Richard A Young, Simon Tavaré, Jacqueline A Lees, Duncan T Odom
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-10-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0001061&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0001061&type=printable

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