How to improve the quality of euglycemic glucose clamp tests in long-acting insulin studies

How to improve the quality of euglycemic glucose clamp tests in long-acting insulin studies

Abstract Background The euglycemic clamp test stands as the best method for assessing the pharmacokinetic and pharmacodynamic properties of long-acting insulin. However, despite its widespread use, there remains a notable absence of an established gold standard for evaluating the test’s quality. Exi...

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Bibliographic Details
Main Authors: Yi Yang, Fu Kuang, XueYing Zhu, Li Li, Yao Huang, Yang Liu, Xian Yu
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Trials
Subjects:
Euglycemic glucose clamp test
Long-acting insulin
Quality control
Healthy volunteers
Blood glucose
C-peptide
Online Access:https://doi.org/10.1186/s13063-025-08749-2
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https://doi.org/10.1186/s13063-025-08749-2

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