Lipocalin-2-mediated ferroptosis as a target for protection against light-induced photoreceptor degeneration

Abstract Background Retinal degeneration is a leading cause of blindness worldwide. The induction of ferroptosis has been identified as an important mechanism contributing to the loss of photoreceptors in retinal degeneration. Lipocalin-2 (LCN2) exhibits iron-regulatory properties and may modulate c...

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Bibliographic Details
Main Authors: Wenyi Tang, Ruyi Zhai, Jun Ma, Gezhi Xu
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Molecular Medicine
Subjects:
Online Access:https://doi.org/10.1186/s10020-025-01250-1
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