MTNR1B variants increase gestational diabetes mellitus risk in young Chinese pregnant women

MTNR1B variants increase gestational diabetes mellitus risk in young Chinese pregnant women

Abstract The aim of this study is to explore the relationship between the MTNR1B gene variants rs1387153 and rs10830963 and the risk of gestational diabetes mellitus (GDM). Additionally, the study sought to investigate gene-environment interactions, assess the cumulative genetic risk through the app...

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Bibliographic Details
Main Authors: Qiaoli Zeng, Xin Liu, Jia Liu, Yanying Wu, Yuxuan Zhang, Zhaotao He, Yue Wei, Guofang Zeng, Dehua Zou, Runmin Guo
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Reports
Subjects:
Gestational diabetes mellitus
MTNR1B polymorphisms
Gene-environment interactions
Genetic risk scores
Predictive model
Online Access:https://doi.org/10.1038/s41598-025-02248-9
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https://doi.org/10.1038/s41598-025-02248-9

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