The role of Apolipoprotein E4 on cognitive impairment in Parkinson’s disease and Parkinsonisms

Cognitive impairment is a prevalent non-motor symptom of Parkinson’s disease (PD), increasing the risk of dementia as the disease progresses. Despite its clinical significance, the etiology of cognitive impairment in PD remains unclear. Apolipoprotein E4 (APOE4), a well-known genetic risk factor of...

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Bibliographic Details
Main Authors: Angenelle Eve Rosal, Sarah L. Martin, Antonio P. Strafella
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1515374/full
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