How Do ROS Induce NETosis? Oxidative DNA Damage, DNA Repair, and Chromatin Decondensation

Neutrophil extracellular traps (NETs) are intricate, DNA-based, web-like structures adorned with cytotoxic proteins. They play a crucial role in antimicrobial defense but are also implicated in autoimmune diseases and tissue injury. The process of NET formation, known as NETosis, is a regulated cell...

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Bibliographic Details
Main Authors: Dhia Azzouz, Nades Palaniyar
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/14/10/1307
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