Mitigative effect of sodium alginate on streptozotocin (STZ)-induced diabetic neuropathy through regulation of redox status and miR-146a in the rat sciatic nerve

Mitigative effect of sodium alginate on streptozotocin (STZ)-induced diabetic neuropathy through regulation of redox status and miR-146a in the rat sciatic nerve

Diabetic peripheral neuropathy (DPN) is a significant complication of diabetes with limited effective therapeutic options. Sodium alginate (SA), a natural polysaccharide from brown algae, has demonstrated health benefits, however, whether it can treat streptozotocin (STZ)-induced DPN remains unclear...

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Bibliographic Details
Main Authors: Nema A. Mohamed, Naeimah M. Shouran, Amina E. Essawy, Ashraf M. Abdel-Moneim, Sherine Abdel Salam
Format: Article
Language:English
Published: PeerJ Inc. 2025-03-01
Series:PeerJ
Subjects:
Sodium alginate
Diabetic neuropathy
Oxidative stress
Inflammation
Apoptosis
MiR-146a
Online Access:https://peerj.com/articles/19046.pdf
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