Synergistic mechanotherapy and sonopermeation guided by mathematical modeling for solid tumor treatment

The progression of tumors and their response to treatment are significantly influenced by the presence of elevated mechanical solid stress. This solid stress compresses intratumoral blood vessels, leading to reduced blood flow (hypoperfusion) and insufficient oxygen levels (hypoxia), both of which h...

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Bibliographic Details
Main Authors: Marina Koutsi, Triantafyllos Stylianopoulos, Fotios Mpekris
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Drug Delivery
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fddev.2025.1549098/full
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