Non-canonical regulation of the reactivation of an oncogenic herpesvirus by the OTUD4-USP7 deubiquitinases.

Non-canonical regulation of the reactivation of an oncogenic herpesvirus by the OTUD4-USP7 deubiquitinases.

Deubiquitinases (DUBs) remove ubiquitin from substrates and play crucial roles in diverse biological processes. However, our understanding of deubiquitination in viral replication remains limited. Employing an oncogenic human herpesvirus Kaposi's sarcoma-associated herpesvirus (KSHV) to probe t...

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Main Authors: Shaowei Wang, Xuezhang Tian, Yaru Zhou, Jun Xie, Ming Gao, Yunhong Zhong, Chuchu Zhang, Keying Yu, Lei Bai, Qingsong Qin, Bo Zhong, Dandan Lin, Pinghui Feng, Ke Lan, Junjie Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011943&type=printable
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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011943&type=printable

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