Contrastive-learning of language embedding and biological features for cross modality encoding and effector prediction

Abstract Identifying and characterizing virulence proteins secreted by Gram-negative bacteria are fundamental for deciphering microbial pathogenicity as well as aiding the development of therapeutic strategies. Effector predictors utilizing pre-trained protein language models (PLMs) have shown sound...

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Bibliographic Details
Main Authors: Yue Peng, Junze Wu, Yi Sun, Yuanxing Zhang, Qiyao Wang, Shuai Shao
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56526-1
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