Single-molecule direct RNA sequencing reveals the shaping of epitranscriptome across multiple species

Single-molecule direct RNA sequencing reveals the shaping of epitranscriptome across multiple species

Abstract N6-methyladenosine (m6A) is an essential RNA modification that regulates gene expression and influences diverse cellular processes. Yet, fully characterizing its transcriptome-wide landscape and biogenesis mechanisms remains challenging. Traditional next-generation sequencing (NGS) methods...

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Main Authors: Ying-Yuan Xie, Zhen-Dong Zhong, Hong-Xuan Chen, Ze-Hui Ren, Yuan-Tao Qiu, Ye-Lin Lan, Fu Wu, Jin-Wen Kong, Ru-Jia Luo, Delong Zhang, Biao-Di Liu, Yang Shu, Feng Yin, Jian Wu, Zigang Li, Zhang Zhang, Guan-Zheng Luo
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60447-4
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https://doi.org/10.1038/s41467-025-60447-4

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