Engineering exosomes from fibroblast growth factor 1 pre-conditioned adipose-derived stem cells promote ischemic skin flaps survival by activating autophagy

Engineering exosomes from fibroblast growth factor 1 pre-conditioned adipose-derived stem cells promote ischemic skin flaps survival by activating autophagy

Background: The recovery of ischemic skin flaps is a major concern in clinical settings. The purpose of this study is to evaluate the effects of engineered exosomes derived from FGF1 pre-conditioned adipose-derived stem cells (FEXO) on ischemic skin flaps. Method: 6 patients who suffered from pressu...

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Bibliographic Details
Main Authors: Xuanlong Zhang, Xiaoqiong Jiang, Huiming Deng, Gaoxiang Yu, Ningning Yang, Abdullah Al Mamun, Feifei Lian, Tianling Chen, Haijuan Zhang, Yingying Lai, Jiayi Huang, Shi Xu, Fuman Cai, Xiaokun Li, Kailiang Zhou, Jian Xiao
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Materials Today Bio
Subjects:
Exosomes
Fibroblast growth factor 1
Autophagy
Skin flaps
GPR137
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424003752
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