The large-scale whole-genome sequencing era expedited medical discovery and clinical translation

Genomic research has been constrained by insufficient diversity over the past two decades, with over 90 ​% of studies targeting populations of European ancestry. This imbalance has hampered health equity and precision medicine, resulting in limited transferability of polygenic risk scores to underre...

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Bibliographic Details
Main Authors: Qingxin Yang, Shuhan Duan, Yuguo Huang, Chao Liu, Mengge Wang, Guanglin He
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:EngMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2950489925000016
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