Current research status on HER2 protein expression levels and the efficacy of targeted therapy in breast cancer

This review summarizes the relationship between HER2 protein expression and the efficacy of three anti-HER2 targeted therapies in breast cancer patients: monoclonal antibodies, antibody-drug conjugates (ADCs), and tyrosine kinase inhibitors (TKIs). The effectiveness of monoclonal antibody therapies...

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Bibliographic Details
Main Authors: Jiani Liu, Xinyu Peng, Yang Yang, Ruixue Yue, Xuhui Huang, Yongtao Du, Chongzhu Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1551415/full
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