Overstretch causes lipid accumulation in vascular smooth muscle cells dependent on NADPH oxidase 1

At the bend and bifurcation of arteries prone to atherosclerosis, pulsatile blood retention may cause overstretch on the tube wall. It has been reported that more than half of the foam cells found in atherosclerotic plaques are derived from vascular smooth muscle cells (VSMCs), but the mechanism is...

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Bibliographic Details
Main Authors: Jiazhen Zhang, Qinfen Li, Suoqi Ding, Wei Xu, Jilei Su, Jingang Cui, Yongsheng Ding
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Mechanobiology in Medicine
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Online Access:http://www.sciencedirect.com/science/article/pii/S2949907025000178
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