Increased inflammatory signature in myeloid cells of non-small cell lung cancer patients with high clonal hematopoiesis burden

Increased inflammatory signature in myeloid cells of non-small cell lung cancer patients with high clonal hematopoiesis burden

Clonal hematopoiesis of indeterminate potential (CHIP) allows estimation of clonal dynamics and documentation of somatic mutations in the hematopoietic system. Recent studies utilizing large cohorts of the general population and patients have revealed significant associations of CHIP burden with age...

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Bibliographic Details
Main Authors: Hyungtai Sim, Hyun Jung Park, Geun-Ho Park, Yeon Jeong Kim, Woong-Yang Park, Se-Hoon Lee, Murim Choi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-12-01
Series:eLife
Subjects:
clonal hematopoiesis
immune checkpoint inhibitor
inflammation
NSCLC
Online Access:https://elifesciences.org/articles/96951
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https://elifesciences.org/articles/96951

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