Early therapeutic drug monitoring of methotrexate and its association with acute kidney injury: A retrospective cohort study

Early therapeutic drug monitoring of methotrexate and its association with acute kidney injury: A retrospective cohort study

Abstract Introduction High‐dose methotrexate (HDMTX) use can be limited by the development of acute kidney injury (AKI). Early AKI detection is paramount to prevent further renal injury and irreversible toxicities. This study sought to determine whether early elimination patterns of MTX would be use...

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Main Authors: Nicolás Tentoni, Miriam Hwang, Gabriela Villanueva, Ryan Combs, Jennifer Lowe, Laura B. Ramsey, Zachary L. Taylor, Thais Murciano Carrillo, María Dolores Aumente, Teresa López‐Viñau López, Carmelo Rizzari, Scott C. Howard
Format: Article
Language:English
Published: Wiley 2024-09-01
Series:Cancer Medicine
Subjects:
acute kidney injury
biomarker
early methotrexate elimination half‐life
high‐dose methotrexate
Online Access:https://doi.org/10.1002/cam4.70176
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