Development, characterization, and replication of proteomic aging clocks: Analysis of 2 population-based cohorts.

Development, characterization, and replication of proteomic aging clocks: Analysis of 2 population-based cohorts.

<h4>Background</h4>Biological age may be estimated by proteomic aging clocks (PACs). Previous published PACs were constructed either in smaller studies or mainly in white individuals, and they used proteomic measures from only one-time point. In this study, we created de novo PACs and co...

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Main Authors: Shuo Wang, Zexi Rao, Rui Cao, Anne H Blaes, Josef Coresh, Rajat Deo, Ruth Dubin, Corinne E Joshu, Benoit Lehallier, Pamela L Lutsey, James S Pankow, Wendy S Post, Jerome I Rotter, Sanaz Sedaghat, Weihong Tang, Bharat Thyagarajan, Keenan A Walker, Peter Ganz, Elizabeth A Platz, Weihua Guan, Anna Prizment
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-09-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1004464
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https://doi.org/10.1371/journal.pmed.1004464

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